A Rare Pleomorphic Adenoma in an Uncommon Area: A Case Report

Document Type : Case Reports

Authors

1 Oral and Maxillofacial Surgeon, Oral and Maxillofacial Surgery Unit, University Hospital of Maracaibo, Venezuela

2 Surgeon Oncologist, Head and Neck Unit, University Hospital of Maracaibo, Venezuela

3 Oral Surgeon, Oral and Maxillofacial Surgery Unit, University Hospital of Maracaibo, Venezuela

Abstract

The Pleomorphic Adenoma is the most frequent benign tumor of the salivary glands. The cheeks, lips and gingiva are rare sites of appearance. The objective of this study is to report a case of a Pleomorphic Adenoma arising from the buccal mucosa. A 57-year-old female patient who presented with an increase in volume in the right facial region with one year of evolution, asymptomatic and without treatment. Physical examination revealed a nodular lesion of approximately 3 cm in diameter, located in the right cheek. MRI revealed a hyperintense image in STIR sequence. Excisional biopsy of the lesion was made under balanced general anesthesia, where extracapsular dissection of the tumor was performed, using a transoral approach. The histopathological study resulted in pleomorphic adenoma. Despite the low rate of recurrence of this neoplasm, short, medium and long term follow-ups are recommended.

Keywords

Main Subjects

References

[1]  Jagadishkumar K, Anilkumar MG, Kumar HC, Maggad R. Pleomorphic adenoma of the cheek in a child: A case report. Dental research journal. 2014;11(4):522.
[2]  Kim YH, Yoon HW, Kim J, Kim SW. Ectopic pleomorphic adenoma on subcutaneous plane of the cheek. Archives of craniofacial surgery. 2019;20(1):55. doi: 10.7181/acfs.2018.01949.
[3]  Erdem MA, Çankaya AB, Güven G, Olgaç V, Kasapoglu C. Pleomorphic adenoma of the palate. Journal of Craniofacial Surgery. 2011;22(3):1131-4. doi: 10.1097/SCS.0b013e3182108f8b.
[4]  Bablani D, Bansal S, Shetty SJ, Desai R, Kulkarni SR, Prasad P, Karjodkar FR. Pleomorphic adenoma of the cheek: a case report and review. Journal of oral and maxillofacial surgery. 2009;67(7):1539-42. DOI:https://doi.org/10.1016/j.joms.2008.07.026.
[5]  Wang DC, Chen Y, Guo CB. Pleomorphic adenoma of the cheek: A case report arising from accessory parotid gland around Stensen's duct orifice. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2016;28(4):341-3.. https://doi.org/10.1016/j.ajoms.2016.02.007.
[6]  Chandhry AD. Intraoral minor salivary gland tumors. An analysis of 1414 cases. Oral Surg Oral Med Oral Pathol. 1961;14:1194-226.
[7]  Ejeil AL, Moreau N, Le Pelletier F. A rare ectopic localization of pleomorphic adenoma. Journal of stomatology, oral and maxillofacial surgery. 2019;120(4):373-4. https://doi.org/10.1016/j.jormas.2018.11.016.
[8]  Urs AB, Augustine J, Negi D, Kumar RD, Ghosh S. Pleomorphic adenoma: a rare presentation in buccal salivary gland with extensive squamous and mucous metaplasia. The Pan African Medical Journal. 2019;33:147. doi:10.11604/pamj.2019.33.147.17550.
[9]  Varghese BT, Sebastian P, Abraham EK, Mathews A. Pleomorphic adenoma of minor salivary gland in the parapharyngeal space. World journal of surgical oncology. 2003;1(1):2.https://doi.org/10.1186/1477-7819-1-2.
[10] Zainab H. Juvenile pleomorphic adenoma: A case report. International Journal of Dental Science and Research. 2013;1(2):70-2. https://doi.org/10.1016/j.ijdsr.2013.11.007.
 [11] Tsegga TM, Britt JD, Ellwanger AR. Pleomorphic adenoma of the accessory parotid gland: case report and reappraisal of intraoral extracapsular dissection for management. Journal of Oral and Maxillofacial Surgery. 2015;73(3):564-70. https://doi.org/10.1016/j.joms.2014.09.015.
[12] Jorge J, Pires FR, Alves FA, Perez DE, Kowalski LP, Lopes MA, Almeida OP. Juvenile intraoral pleomorphic adenoma: report of five cases and review of the literature. International journal of oral and maxillofacial surgery. 2002;31(3):273-5. https://doi.org/10.1054/ijom.2002.0206.
[13] Lingam RK, Daghir AA, Nigar E, Abbas SA, Kumar M. Pleomorphic adenoma (benign mixed tumour) of the salivary glands: its diverse clinical, radiological, and histopathological presentation. British Journal of Oral and Maxillofacial Surgery. 2011;49(1):14-20. https://doi.org/10.1016/j.bjoms.2009.09.014.
[14] Isacsson G, Shear M. Intraoral salivary gland tumors: a retrospective study of 201 cases. Journal of Oral Pathology & Medicine. 1983;12(1):57-62. https://doi.org/10.1111/j.1600-0714.1983.tb00316.x.
[15] Fine G, Marshall RB. Horn. R. C, Jr. Tumors of the minor salivary glands. Cancer. 1960;13:653-67.
[16] Main JH, Orr JA, McGurk FM, McComb RJ, Mock D. Salivary gland tumors: review of 643 cases. Journal of Oral Pathology & Medicine. 1976;5(2):88-102. https://doi.org/10.1111/j.1600-0714.1976.tb01870.x.
[17] Cohen MA. Pleomorphic adenoma of the cheek. International journal of oral and maxillofacial surgery. 1986;15(6):777-9. https://doi.org/10.1016/S0300-9785(86)80123-5.
[18] Buchner A, Merrell PW, Carpenter WM. Relative frequency of intra‐oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. Journal of oral pathology & medicine. 2007;36(4):207-14. https://doi.org/10.1111/j.1600-0714.2007.00522.x.
[19] Lopes MA, Kowalski LP, Cunha Santos G, De Almeida OP. A clinicopathologic study of 196 intraoral minor salivary gland tumours. Journal of oral pathology & medicine. 1999;28(6):264-7. https://doi.org/10.1111/j.1600-0714.1999.tb02036.x.
[20] Yih WY, Kratochvil FJ, Stewart JC. Intraoral minor salivary gland neoplasms: review of 213 cases. Journal of oral and maxillofacial surgery. 2005;63(6):805-10. https://doi.org/10.1016/j.joms.2005.02.021.
[21] Hayashi Y, Iwai T, Sugiyama S, Osawa K, Yoshii H, Minamiyama S, Kitajima H, Hirota M, Mitsudo K. Intra-oral minor salivary gland tumors: A pathological study of 131 cases in the Japanese population. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2019;31(6):424-7. https://doi.org/10.1016/j.ajoms.2019.06.007.
[22] Pérez-de-Oliveira ME, Leonel AC, de Castro JF, Carvalho EJ, Vargas PA, Perez DE. Histopathological Findings of Intraoral Pleomorphic Adenomas: A Retrospective Study of a Case Series. International journal of surgical pathology. 2019;27(7):729-35. https://doi.org/10.1177/1066896919854181.
[23] Toida M, Shimokawa K, Makita H, Kato K, Kobayashi A, Kusunoki Y, Hatakeyama D, Fujitsuka H, Yamashita T, Shibata T. Intraoral minor salivary gland tumors: a clinicopathological study of 82 cases. International journal of oral and maxillofacial surgery. 2005;34(5):528-32. https://doi.org/10.1016/j.ijom.2004.10.010.
[24] Rivera‐Bastidas H, Ocanto RA, Acevedo AM. Intraoral minor salivary gland tumors: a retrospective study of 62 cases in a Venezuelan population. Journal of oral pathology & medicine. 1996;25(1):1-4. https://doi.org/10.1111/j.1600-0714.1996.tb01214.x.
[25] Periasamy S, Manoharan A, Garg H, Kumar SP. Pleomorphic Adenoma of the Cheek: A Case Report. Cureus. 2019;11(8):e5312. doi: 10.7759/cureus.5312.
International Journal of Scientific Research in Dental and Medical Sciences
Volume 2, Issue 2
June 2020
Pages 59-62

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History

  • Receive Date: 24 March 2020
  • Revise Date: 16 May 2020
  • Accept Date: 26 May 2020

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