International Journal of Scientific Research in Dental and Medical Sciences

International Journal of Scientific Research in Dental and Medical Sciences

Incidental Serous Tubal Intraepithelial Carcinoma: A Case Report

Document Type : Case Reports

Authors
Prachi Arun
Nikita Prasad
Anu Sahjlan
Anjum Bhukal
Manika Yadav
Aditi Baghla
Department of Pathology, Maharaja Agrasen Medical College, Agroha, India
10.30485/ijsrdms.2025.535597.1667
Abstract
High-grade pelvic serous carcinoma (HGSC) is the most common type of pelvic cancer among females. Serous tubal intraepithelial carcinoma (STIC) is an established precursor of HGSC, albeit rare and underdiagnosed. Its incidence ranges from <0.01% to 3% in BRCA carriers or those with a strong family history of breast or ovarian cancer. A 32 32-year-old P2L2 female underwent bilateral tubectomy for family planning, with no known family history of cancer. Histopathological examination of the fallopian tube revealed unilateral STIC. Incidental STIC mandates prolonged follow-up. Diagnosing tubal precursor lesions (such as SCOUT, STIL, STIC) to HGSC is crucial in identifying at-risk patients. The SEE-FIM protocol, along with a low immunohistochemistry threshold, is recommended. Due to its rarity and challenging diagnostic criteria, a high degree of suspicion on the part of pathologists and adequate follow-up are essential to reduce morbidity and mortality.
Keywords
Carcinoma
Fallopian Tubes
Ovarian Neoplasms

Subjects

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International Journal of Scientific Research in Dental and Medical Sciences
Volume 7, Issue 3
Summer 2025
Pages 128-130

  • Receive Date 02 July 2025
  • Revise Date 14 August 2025
  • Accept Date 23 August 2025
  • Publish Date 01 September 2025