Evaluation of the Effect of Zirconium Dioxide Nanoparticles on the Flexural Properties of Polymerized Acrylic Resin for Interim Fixed Restorations: Α Systematic Review and Meta-analysis

Document Type : Review Article


1 Department of Prosthodontics, Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran

2 Independent Researcher, Sanandaj, Iran

3 Department of Prosthodontics, Faculty of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

4 Independent Researcher, Shiraz, Iran


Background and aim: Interim restorations are one of the important steps in placing fixed dental prostheses. Their mechanical and biological properties should be checked, and they should also be checked in terms of aesthetics. The current investigation aims to ascertain the impact of ZrO2 nanoparticle addition on the flexural strength of acrylic resins when utilized for interim fixed restorations.
Material and methods: Using search terms associated with the study's goals, all worldwide databases, including PubMed, Science Direct, Scopus, ISI, and Embase, as well as Web of Knowledge, were investigated till May 2023. The fixed effect model and inverse-variance methodology have been utilized to get a confidence interval of 95% for mean differences. The meta-analysis has been carried out with Stata/MP v.17 software.
Results: The original review, which also examined the abstracts of 95 papers, was cleaned up of duplicate research. Two writers carefully assessed sixteen papers, and four studies were ultimately chosen. The mean difference in flexural strength between 0.5-ZrO2 and the control group was 24.07 (MD; 95 CI (20.72, 27.42), p<0.05). The 5-ZrO2 group had the lowest value of flexural strength, which was 0.14 (MD=0.14; 95 CI (-2.51, 2.80), p>0.05). The PMMA pristine interim restorative material's flexural strength values were dramatically enhanced by the addition of ZrO2 (2.5 wt%) (MD=5.03; 95 CI (2.65, 7.14), p<0.05).
Conclusions: The highest flexural strength value was related to specimens reinforced with 0.5, 1, and 2.5-wt% ZrO2 nanoparticles.


Main Subjects

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