International Journal of Scientific Research in Dental and Medical Sciences

International Journal of Scientific Research in Dental and Medical Sciences

Tailored Vascular Reconstruction Strategies for Multiple Renal Arteries in Living Donor Kidney Transplantation: A Case Series

Document Type : Case Reports

Authors
1 Department of General Surgery, Division of Organ Transplant, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
2 Department of General Medicine, Division of Nephrology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
3 Department of Urology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
4 Department of Anesthesia and Pain Medicine, Division of Organ Transplant Anesthesia, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
Abstract
Kidney transplantation remains the treatment of choice for patients with end-stage kidney disease (ESKD); however, grafts with multiple renal arteries (MRA) continue to pose technical challenges because of their complex vascular anatomy. This study aimed to describe our institutional experience with individualized vascular reconstruction strategies for living-donor kidneys with complex arterial anatomy and to evaluate their early clinical outcomes. We retrospectively reviewed six consecutive living-donor kidney transplantations performed between October 2021 and February 2023 involving grafts with dual, triple, or early arterial branching. The vascular reconstruction technique was selected based on the anatomical configuration. It included pantaloon reconstruction for closely spaced arteries, separate end-to-side anastomoses for widely spaced vessels, and an inferior epigastric artery anastomosis for distant polar arteries before implantation into the external iliac vessels. All six recipients (five males and one female; mean age, 35.5 years) demonstrated immediate graft perfusion and prompt urine output following transplantation, with progressive improvement in renal function and a mean discharge serum creatinine of 1.16 mg/dL (range, 0.72–1.60 mg/dL). No major postoperative complications, including vascular thrombosis, urinary leakage, delayed graft function, or acute rejection, were observed, and all patients were discharged between postoperative days 5 and 8 with stable graft function. These findings demonstrate that meticulous preoperative planning and individualized vascular reconstruction based on arterial anatomy enable the safe transplantation of kidneys with multiple renal arteries and provide excellent short-term outcomes, supporting the broader utilization of these anatomically complex grafts to expand the living-donor pool.
Keywords
Subjects

[1] Triantafyllou G, Paschopoulos I, Węgiel A, Olewnik Ł, Tsakotos G, Zielinska N, et al. The accessory renal arteries: a systematic review with meta‐analysis. Clinical Anatomy. 2025 Sep;38(6):660-72. https://doi.org/10.1002/ca.24255.
[2] Dimitroulis D, Bokos J, Zavos G, Nikiteas N, Karidis NP, Katsaronis P, et al. Vascular complications in renal transplantation: a single-center experience in 1367 renal transplantations and review of the literature. Transplant Proc. 2009;41(5):1609-14. doi: 10.1016/j.transproceed.2009.02.077.
[3] Lim EJ, Fong KY, Li J, Chan YH, Aslim EJ, Ng LG, et al. Single versus multiple renal arteries in living donor kidney transplantation: A systematic review and patient‐level meta‐analysis. Clinical Transplantation. 2023;37(11):e15069. https://doi.org/10.1111/ctr.15069.
[4] Aydin C, Berber I, Altaca G, Yigit B, Titiz I. The outcome of kidney transplants with multiple renal arteries. BMC surgery. 2004;4(1):4. https://doi.org/10.1186/1471-2482-4-4.
[5] Moreno-Alarcón C, Server-Pastor G, López-González PÁ, López-Cubillana P, Ruiz-Morcillo JC, Doñate-Iñíguez G, et al. Must we still be worried about multiple arteries in kidney transplantation?. Nephro-urology monthly. 2012;5(1):692-6. https://doi.org/10.5812/numonthly.4928.
[6] Moore KL, Persaud TV, Torchia MG. The developing human: clinically oriented embryology. Elsevier Brasil; 2008.
[7] Tiwari B, Pandey P. Various techniques and outcomes of arterial anastomosis in live renal transplant: an institutional experience. Cureus. 2022;14(5):e25262. https://doi.org/10.7759/cureus.25262.
[8] Zorgdrager M, Krikke C, Hofker SH, Leuvenink HG, Pol RA. Multiple renal arteries in kidney transplantation: a systematic review and meta-analysis. Annals of transplantation. 2016;21:469-78. https://doi.org/10.12659/aot.898748.
[9] Özkan U, Oguzkurt L, Tercan F, Kizilkilic O, Koç Z, Koca N. Renal artery origins and variations: angiographic evaluation of 855 consecutive patients. Diagnostic and interventional Radiology. 2006;12(4):183-6.
[10] Benedetti E, Troppmann C, Gillingham K, Sutherland DE, Payne WD, Dunn DL, et al. Short-and long-term outcomes of kidney transplants with multiple renal arteries. Annals of surgery. 1995;221(4):406-14.
[11] Yildirim M, Kucuk HF. Outcomes of renal transplantations with multiple vessels. InTransplantation proceedings 2011;43(3):816-818. https://doi.org/10.1016/j.transproceed.2010.11.017.
Volume 7, Issue 4
Autumn 2025
Pages 197-202

  • Receive Date 10 October 2025
  • Revise Date 13 November 2025
  • Accept Date 24 November 2025
  • Publish Date 01 December 2025