ORIGINAL_ARTICLE
Histologic Evaluation of New Doxycycline Gel Formulation for Subgingival Application in Experimental Periodontitis in Rats
Background and aim: Adjunctive therapy can increase periodontal treatments' success, and to date, various drugs had been suggested. This study aimed to test the efficacy of a new formulation of locally delivered- slow-releasing 10% doxycycline (DOX) gel as a thermogelating system by histologic evaluation in rats with experimental periodontitis.Materials and methods: Periodontal disease was induced with a ligature in maxillary left and right upper first molars of twenty male Sprague-Dawley rats in a seven-day duration. Left molars were treated with DOX gel while the right ones received vehicle drug in the subgingival area. Animals were randomly divided into two groups (each group contained ten rats). One group received the drug only once, while the second one was treated with twice the drug's application. After seven days, animals were killed and prepared for histologic evaluation.Results: Application of DOX gel reduced the degree of inflammation, presence of osteoclasts and resorptive lacuna, and the amount of disorientated collagen fibres after one week compared to teeth treated with vehicle drug (p <0.05) after twice application of the drug no adverse effect and necrotic changes were detected in histologic evaluations.Conclusion: This novel formulation of DOX gel is an effective and safe drug for treating periodontal disease in rats. It seems that the drug can be tested in human clinical trials as an adjunctive treatment for periodontal disease.
http://www.ijsrdms.com/article_119609_51348fd5647d8338e2a7fd9bc464ce90.pdf
2020-12-01
107
114
10.30485/ijsrdms.2020.247105.1084
Doxycycline
histology
Periodontitis
Ali Mohammad
Tamaddon
ali_tamaddon@yahoo.com
1
Center for Nanotechnology in Drug Delivery, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Fars, Iran
AUTHOR
Faezeh
Saadati
faezeh2011@gmail.com
2
Department of Periodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
LEAD_AUTHOR
Hengameh
Khosropanah
khosropanah979@yahoo.com
3
Department of Periodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
AUTHOR
Ali
Dehghani Nazhvani
alidehghaninazhvani@yahoo.com
4
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Fars, Iran
AUTHOR
Gholam Hossein
Yousefi
ghyousefi@sums.ac.ir
5
Center for Nanotechnology in Drug Delivery, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Fars, Iran
AUTHOR
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[16] D'El Rey-Dantas FT, Feijó LS, Nogueira CE, Curcio BD. Doxycycline: a review regarding properties and clinical use in the equine species. Science and Animal Health. 2018;6(2):101-13.
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[19] Rawla P, Raj JP. Doxycycline-induced acute pancreatitis: a rare adverse event. Gastroenterology research. 2017;10(4):244. doi: 10.14740/gr838w.
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[21] Michalova E, Novotna P, Schlegelova J. Tetracyclines in veterinary medicine and bacterial resistance to them. A review. Veterinarni Medicina-UZPI (Czech Republic). 2004.
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[22] ALI IBRAHIM ES, Ismail S, Fetih G, Shaaban O, Hassanein K, Abdellah NH. Development and characterization of thermosensitive pluronic-based metronidazole in situ gelling formulations for vaginal application. Acta pharmaceutica. 2012;62(1):59-70. https://doi.org/10.2478/v10007-012-0009-y.
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[23] Escobar-Chávez JJ, López-Cervantes M, Naik A, Kalia Y, Quintanar-Guerrero D, Ganem-Quintanar A. Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations. Journal of Pharmacy & Pharmaceutical Sciences. 2006;9(3):339-58.
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[24] Shriky B, Kelly A, Isreb M, Babenko M, Mahmoudi N, Rogers S, Shebanova O, Snow T, Gough T. Pluronic F127 thermosensitive injectable smart hydrogels for controlled drug delivery system development. Journal of Colloid and Interface Science. 2020;565:119-30. https://doi.org/10.1016/j.jcis.2019.12.096.
24
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[26] Gupta R, Pandit N, Aggarwal S, Verma A. Comparative evaluation of subgingivally delivered 10% doxycycline hyclate and xanthan-based chlorhexidine gels in the treatment of chronic periodontitis. J Contemp Dent Pract. 2008;9(7):25-32.
26
[27] Wennström JL, Newman HN, MacNeill SR, Killoy WJ, Griffiths GS, Gillam DG, Krok L, Needleman IG, Weiss G, Garrett S. Utilisation of locally delivered doxycycline in non‐surgical treatment of chronic periodontitis: A comparative multi‐centre trial of 2 treatment approaches. Journal of clinical periodontology. 2001;28(8):753-61. https://doi.org/10.1034/j.1600-051X.2001.280806.x.
27
[28] Machion L, Andia DC, Lecio G, Nociti Jr FH, Casati MZ, Sallum AW, Sallum EA. Locally delivered doxycycline as an adjunctive therapy to scaling and root planing in the treatment of smokers: A 2‐year follow‐up. Journal of periodontology. 2006;77(4):606-13. https://doi.org/10.1902/jop.2006.050087.
28
[29] Bogren A, Teles RP, Torresyap G, Haffajee AD, Socransky SS, Wennström JL. Locally delivered doxycycline during supportive periodontal therapy: a 3-year study. Journal of periodontology. 2008;79(5):827-35. https://doi.org/10.1902/jop.2008.070515.
29
[30] Madi M, Pavlic V, Samy W, Alagl A. The anti-inflammatory effect of locally delivered nano-doxycycline gel in therapy of chronic periodontitis. Acta Odontologica Scandinavica. 2018;76(1):71-6. https://doi.org/10.1080/00016357.2017.1385096.
30
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33
[34] Lohinai Z, Benedek P, Fehér E, Györfi A, Rosivall L, Fazekas Á, Salzman AL, Szabó C. Protective effects of mercaptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature‐induced periodontitis in the rat. British journal of pharmacology. 1998;123(3):353-60. https://doi.org/10.1038/sj.bjp.0701604.
34
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35
[36] Woutersen RA, Jonker D, Stevenson H, Te Biesebeek JD, Slob W. The benchmark approach applied to a 28-day toxicity study with Rhodorsil Silane in rats: the impact of increasing the number of dose groups. Food and Chemical Toxicology. 2001;39(7):697-707. https://doi.org/10.1016/S0278-6915(01)00015-1.
36
ORIGINAL_ARTICLE
Perception of Equivalence Between Online and Face-to-face Academic Activities by Undergraduate Medical Students During COVID-19 Pandemic
Background and aim: As online teaching continues to grow in recent years and COVID-19 Pandemic lockdown enforced medical education for online classes in most of the countries, including India, so it is important to investigate medical student's overall Perception about online teaching environments compared to face-to-face (F2F) teaching.Materials and methods: A study was conducted to evaluate the Perception of undergraduate medical students about online teaching. An observational study initiated during lockdown period in April 2020 in a new medical college running in the second year and only two batches available with a total strength of 330 student's attending classes through online mode from the last five months during COVID-19 Pandemic and 295 students were voluntarily participated in the study depending on exclusion and inclusion criteria. The authors measured the student's Perceptions through a pretested questionnaire by assessing their level of interaction, Small Group Teaching (SGT), understanding concepts, knowledge acquired, and conducive environment for learning online courses compared to face-to-face (F2F) courses by using a 5-point Likert scale.Results: Students' overall Perception of online classes conducted in terms of interaction, SGT, knowledge acquired, concepts, and conducive environment for learning was negative compared to Face-to-face (F2F) teaching mode.Conclusion: From a small study, it is very well evidence that students are not able to enjoy online teaching in comparison to face-to-face (F2F) teaching, but online teaching methods can be used as an additional tool instead of replacing it with face-to-face (F2F) classes, particularly in medical education to develop a hybrid curriculum.
http://www.ijsrdms.com/article_119797_c585799c93fced4c6e2b4488c349664b.pdf
2020-12-01
115
120
10.30485/ijsrdms.2020.253310.1091
COVID-19
Face to Face classes
Online Learning
student’s perception
Undergraduate MBBS Students
Jagdish
Hundekari
jchpune@gmail.com
1
Department of Physiology, Government medical college, Ratlam, India
LEAD_AUTHOR
Rahul
Mittal
drrahulmittal13@gmail.com
2
Department of Physiology, Government medical college, Ratlam, India
AUTHOR
Sanjay
Wasnik
jchundekari_31@yahoo.co.in
3
Department of Physiology, Government medical college, Ratlam, India
AUTHOR
Lokendra
Kot
lskot1972@gmail.com
4
Department of community medicine, Government medical college, Ratlam, India
AUTHOR
[1] Parry, M. Colleges see 17 percent increase in online enrolment. The Chronicle of Higher Education.http://chronicle.com/blogs/wiredcampus/colleges-see-17-percent-increase-in-online-enrollment. 2011.
1
[2] Parker K, Lenhart A, Moore K. The digital revolution and higher education: College presidents, public differ on value of online learning. Pew Internet & American Life Project. 2011.
2
[3] Kaya T. Enrollment in online courses increases at the highest rate ever. Chronicle of Higher Education. 2010.
3
[4] Allen TH. Is the rush to provide on-line instruction setting our students up for failure?. Communication Education. 2006;55(1):122-6. https://doi.org/10.1080/03634520500343418.
4
[5] Allen IE, Seaman J. Grade change: Tracking online education in the United States. Babson Park, MA: Babson Survey Research Group.2014.
5
[6] Benoit PJ, Benoit W, Milyo J, Hansen G. The effects of traditional vs. web-assisted instruction on student learning and satisfaction. Report published by the University of Missouri. 2006.
6
[7] Bernard RM, Abrami PC, Lou Y, Borokhovski E, Wade A, Wozney L, Wallet PA, Fiset M, Huang B. How does distance education compare with classroom instruction? A meta-analysis of the empirical literature. Review of educational research. 2004;74(3):379-439. https://doi.org/10.3102/00346543074003379.
7
[8] Jahng N, Krug D, Zhang Z. Student achievement in online distance education compared to face-to-face education. European Journal of Open, Distance and E-Learning. 2007;10(1).
8
[9] Sitzmann T, Kraiger K, Stewart D, Wisher R. The comparative effectiveness of web‐based and classroom instruction: A meta‐analysis. Personnel psychology. 2006;59(3):623-64. https://doi.org/10.1111/j.1744-6570.2006.00049.x.
9
[10] Pei L, Wu H. Does online learning work better than offline learning in undergraduate medical education? A systematic review and meta-analysis. Medical education online. 2019;24(1):1666538. https://doi.org/10.1080/10872981.2019.1666538.
10
[11] Kilgo CA, Sheets JE, Pascarella ET. Do high-impact practices actually have high-impact on student learning? Some initial findings. Inannual conference of the Association for the Study of Higher Education, St. Louis, MO 2013.
11
[12] Lizzio A, Wilson K, Simons R. University students' perceptions of the learning environment and academic outcomes: implications for theory and practice. Studies in Higher education. 2002;27(1):27-52. https://doi.org/10.1080/03075070120099359.
12
[13] Sherblom JC. The computer-mediated communication (CMC) classroom: A challenge of medium, presence, interaction, identity, and relationship. Communication Education. 2010;59(4):497-523. https://doi.org/10.1080/03634523.2010.486440.
13
[14] Centers for Disease Control and Prevention. Division of Health Informatics and Surveillance. National notifiable diseases surveillance system. Atlanta, GA: Available at: https://www. cdc. gov/mmwr/mmwr_nd/nd_data_tables. html. Accessed. 2017.
14
[15] Faux TL, Black-Hughes C. A comparison of using the Internet versus lectures to teach social work history. Research on social work practice. 2000;10(4):454-66. https://doi.org/10.1177/104973150001000406.
15
[16] Leasure AR, Davis L, Thievon SL. Comparison of student outcomes and preferences in a traditional vs. world wide web-based baccalaureate nursing research course. Journal of Nursing Education. 2000;39(4):149-54. https://doi.org/10.3928/0148-4834-20000401-04.
16
[17] Parry M. Will Technology Kill the Academic Calendar? chronicle. 2010.
17
[18] Sahu PK, Nayak S, Rodrigues V. Medical students’ perceptions of small group teaching effectiveness in hybrid curriculum. Journal of education and health promotion. 2018. doi: 10.4103/jehp.jehp_71_17.
18
[19] Jaques D. Teaching small groups. Bmj. 2003;326(7387):492-4.
19
[20] Mentzer G, Cryan J, Teclehaimanot B. Two peas in a pod? A comparison of face-to-face and web based classrooms. Journal of Technology and Teacher Education. 2007;15(2):233-46.
20
[21] Horspool A, Yang SS. A comparison of university student perceptions and success learning music online and face-to-face. MERLOT Journal of Online Learning and Teaching. 2010;6(1):15-29.
21
[22] Platt CA, Amber NW, Yu N. Virtually the same?: Student perceptions of the equivalence of online classes to face-to-face classes. Journal of Online Learning and Teaching. 2014;10(3):489.
22
[23] Davis BG. Tools for teaching. John Wiley & Sons; 2009.
23
[24] McKeachie WJ, Svinicki M. Problem-based learning: Teaching with cases, simulations, and games. McKeachie’s Teaching Tips: Strategies, Research, and Theory for College and University Teachers, 12th ed. Boston, MA: Houghton Mifflin. 2006:222-5.
24
ORIGINAL_ARTICLE
Accuracy of Panoramic Radiography in Assessing the Labio-palatal Position of Maxillary Impacted Canines and Root Resorption of the Adjacent Tooth
Background and aim: Determining the accuracy of panoramic radiography in assessing the labio-palatal position of maxillary impacted canines and root resorption of the adjacent tooth.Materials and methods: We used these further variables: angulation, mesiodistal position, and vertical position, which respectively were based on the angulation of canine about the midsagittal plane, five sectors on panoramic radiographs using the Allcandri method, and division of incisor adjacent to the impacted canine into three sectors. labio-palatal position of the MICs and root resorption of permanent incisors were evaluated on CBCT. The statistical correlation between the investigated variables on panoramic and position of MICs and the root resorption of the adjacent tooth on CBCT were examined using independent t-test, Mann-Whitney test, and Fisher's exact test.Results: In respect of the mesiodistal position of the cusp tip of the MIC, the labially localized MICs were common in sectors 1 and 2, and the palatally localized MICs were more frequent in sectors 3, 4, and 5. Concerning the vertical position of the MIC's cusp tip, the localized labial MICs were more common in sectors 1 and 3, and palatally localized MICs were more frequent in sector 2. The mean angle of MICs about the sagittal plane was significantly higher in the palatally localized MICs. There was no significant correlation between the MIC's tip, mesiodistal position, and the adjacent tooth's root resorption.Conclusion: Results showed the correlation coefficients among the upper pharyngeal airway width, and ANB and Witt's analyses were not significant. These results can reinforce the probability of class III malocclusion inheritance.
http://www.ijsrdms.com/article_120370_1004c9fdecaedecba665c1366f8a3060.pdf
2020-12-01
121
125
10.30485/ijsrdms.2020.254092.1093
Canine Tooth
CBCT
Impacted tooth
Panoramic radiography
Root resorption
Zahra Sadat
Tabatabaei Jebeli
ztabatabaei2@gmail.com
1
School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
LEAD_AUTHOR
Mehdi
Rafiei
mehdirafiei@gmail.com
2
Department of Orthodontics, School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
AUTHOR
Azadeh
Torkzadeh
azadehtorkzadeh@yahoo.com
3
Department of Oral and Maxillofacial Radiology, School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
AUTHOR
[1] Al-Zoubi H, Alharbi AA, Ferguson DJ, Zafar MS. Frequency of impacted teeth and categorization of impacted canines: A retrospective radiographic study using orthopantomograms. European journal of dentistry. 2017;11(1):117-121. doi: 10.4103/ejd.ejd_308_16.
1
[2] Lai CS, Suter VG, Katsaros C, Bornstein MM. Localization of impacted maxillary canines and root resorption of neighbouring teeth: a study assessing the diagnostic value of panoramic radiographs in two groups of observers. European journal of orthodontics. 2014;36(4):450-6. https://doi.org/10.1093/ejo/cjt074.
2
[3] Izadikhah I, Cao D, Zhao Z, Yan B. Different Management Approaches in Impacted Maxillary Canines: An Overview on Current Trends and Literature. The Journal of Contemporary Dental Practice. 2020;21(3):326-36.
3
[4] Alqerban A, Jacobs R, Fieuws S, Willems G. Comparison of two cone beam computed tomographic systems versus panoramic imaging for localization of impacted maxillary canines and detection of root resorption. The European Journal of Orthodontics. 2011;33(1):93-102. https://doi.org/10.1093/ejo/cjq034.
4
[5] Ngo CT, Fishman LS, Rossouw PE, Wang H, Said O. Correlation between panoramic radiography and cone-beam computed tomography in assessing maxillary impacted canines. The Angle Orthodontist. 2018;88(4):384-9. https://doi.org/10.2319/103117-739.1.
5
[6] Sajnani AK. Permanent maxillary canines–review of eruption pattern and local etiological factors leading to impaction. Journal of investigative and clinical dentistry. 2015;6(1):1-7. https://doi.org/10.1111/jicd.12067.
6
[7] Elmarhoumy S, Gomaa N. Assessment of maxillary impacted canines using panoramic radiograph and cone-beam computed tomography. Egyptian Dental Journal.2020;66(4):2015-2019.DOI: 10.21608/edj.2020.39553.1213.
7
[8] Christell H, Birch S, Bondemark L, Horner K, Lindh C, SEDENTEXCT consortium. The impact of Cone Beam CT on financial costs and orthodontists’ treatment decisions in the management of maxillary canines with eruption disturbance. European journal of orthodontics. 2018;40(1):65-73. https://doi.org/10.1093/ejo/cjx039.
8
[9] El Beshlawy DM. Radiographic assessment of impacted maxillary canine position using CBCT: A comparative study of 2 methods. Egyptian Dental Journal.2019;65(4):3393-402. DOI: 10.21608/edj.2019.74780.
9
[10] Eslami E, Barkhordar H, Abramovitch K, Kim J, Masoud MI. Cone-beam computed tomography vs conventional radiography in visualization of maxillary impacted-canine localization: A systematic review of comparative studies. American Journal of Orthodontics and Dentofacial Orthopedics. 2017;151(2):248-58. https://doi.org/10.1016/j.ajodo.2016.07.018.
10
[11] Alhammadi MS, Asiri HA, Almashraqi AA. Incidence, severity and orthodontic treatment difficulty index of impacted canines in Saudi population. Journal of clinical and experimental dentistry. 2018;10(4):e327.
11
[12] Nagpal A, Pai KM, Setty S, Sharma G. Localization of impacted maxillary canines using panoramic radiography. Journal of oral science. 2009;51(1):37-45. https://doi.org/10.2334/josnusd.51.37.
12
[13] Kanwar A. Evaluation of positionof maxillary impacted canine and its effect on adjacent teeth-A correlation study between panoramic radiography and cone beam computed tomography. International Journal of Biomedical and Advance Research 2016; 7(9): 472-476. http://dx.doi.org/10.7439/ijbar.
13
[14] Alfaleh W, Al Thobiani S. Evaluation of Impacted Maxillary Canine Position Using Panoramic Radiography and Cone Beam Computed Tomography. The Saudi Dental Journal. 2020. https://doi.org/10.1016/j.sdentj.2020.03.014.
14
[15] Bhuvaneshwari AJ, Singh MP. Use of panoramic radiograph as a single radiographic technique to localize impacted maxillary canine. J Cancer Sci Ther. 2010;2(6):163-5.
15
ORIGINAL_ARTICLE
COVID-19 in Pediatric Patients: A Literature Review
This article aims to review the features of COVID-19 in children and whatever dentists need to perform to protect themselves, their young patients, and staff. A new form of coronavirus infection occurred in Wuhan, China, in mid-December 2019, and it has quickly spread to almost the whole world. Although COVID-19 was primarily more common among adults over 15 years old at the initial steps of the outbreak, and the percentage of children's confirmed cases was fairly low, the new guidelines show that all people, including children, are typically vulnerable to SARS-CoV-2. Also, we should take patients' behaviors and reactions to COVID-19 into consideration during this pandemic situation. Since preventing the transmission of SARS CoV-2 to children and transmission from infected children or parents to healthcare professionals are important, infection prevention checklists and all the points that this study prepared should be used by the whole dentists.
http://www.ijsrdms.com/article_118109_56b55b7fc061f5e90129f39e4aa67679.pdf
2020-12-01
126
130
10.30485/ijsrdms.2020.246164.1083
COVID-19
Epidemiology
Infection Control
Pediatric Dentistry
Maryam
Baghizadeh Fini
m.baghizadeh92@gmail.com
1
Department of Health Promotion, Oklahoma State University, Stillwater, OK, USA
LEAD_AUTHOR
Bahman
Seraj
serajbah@tums.ac.ir
2
Department of Pediatrics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Sara
Ghadimi
sghadimi@sina.tums.ac.ir
3
Department of Pediatrics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
[1] Fini MB. What dentists need to know about COVID-19. Oral Oncology. 2020;105:104741. https://doi.org/10.1016/j.oraloncology.2020.104741.
1
[2] World Health Organization. Coronavirus disease ( COVID-19): weekly epidemiological.2020.
2
[3] Jiatong S, Wenjun L. Epidemiological characteristics and prevention and control measures of Corona Virus Disease 2019 in children. J Trop Med. 2020;20(2):153-6.
3
[4] Kochhar AS, Bhasin R, Kochhar GK, Dadlani H. Covid-19 pandemic and dental practice. International Journal of Dentistry. 2020;2020. https://doi.org/10.1155/2020/8894794.
4
[5] Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang ZJ. Novel coronavirus infection in hospitalized infants under 1 year of age in China. Jama. 2020;323(13):1313-4. doi:10.1001/jama.2020.2131.
5
[6] Centers for Disease Control and Prevention, Care for Children [internet]. [updated 2020 Aug 19]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/pediatric-hcp.html
6
[7] Covid CD, COVID C, COVID C, Bialek S, Gierke R, Hughes M, McNamara LA, Pilishvili T, Skoff T. Coronavirus Disease 2019 in Children—United States, February 12–April 2, 2020. Morbidity and Mortality Weekly Report. 2020;69(14):422-426. doi: 10.15585/mmwr.mm6914e4.
7
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[15] Kong F, Wang A, He J, Xiong L, Xie D, Su J, Liu Z. Trend of unintentional suffocation death for infants under 1 year of age from 2009 to 2018 in Hunan, China: a cross-sectional study. BMJ open. 2020;10(12):e038666. http://dx.doi.org/10.1136/bmjopen-2020-038666.
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[20] Fini MB. Oral saliva and CVID-19. Oral Oncology. 2020:104821. https://doi.org/10.1016/j.oraloncology.2020.104821.
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[21] Lin J, Duan J, Tan T, Fu Z, Dai J. The isolation period should be longer: lesson from a child infected with SARS‐CoV‐2 in Chongqing, China. Pediatric pulmonology. 2020;55(6):E6-9. https://doi.org/10.1002/ppul.24763.
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[24] Gautret P, Lagier JC, Parola P, Meddeb L, Mailhe M, Doudier B, Courjon J, Giordanengo V, Vieira VE, Dupont HT, Honoré S. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International journal of antimicrobial agents. 2020;56(1):105949. https://doi.org/10.1016/j.ijantimicag.2020.105949.
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[26] Ludvigsson JF. Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adults. Acta Paediatrica. 2020;109(6):1088-95. https://doi.org/10.1111/apa.15270.
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[27] Guo H, Zhou Y, Liu X, Tan J. The impact of the COVID-19 epidemic on the utilization of emergency dental services. Journal of Dental Sciences. 2020. https://doi.org/10.1016/j.jds.2020.02.002.
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34
ORIGINAL_ARTICLE
Regenerative Endodontic Treatment in Teeth with Internal Root Resorption: An Insight Over the Available Literature
Internal root resorption (IRR) is a resorptive defect of the root's internal aspect, and its pathogenesis occurs because of the activity of odontoclasts. If left untreated, IRR will eventually cause necrosis of the pulp tissue apical to the resorptive lesion, leading to periapical pathologies and resistance failure of the tooth. Treatment of this kind of pathology encompasses many options ranging from conventional root canal treatment to endodontic surgery. The most recent innovation for the treatment of IRR is revascularization. The present review aims to discuss revascularization as a treatment option for IRR. An extensive search for recent available data regarding this kind of treatment and potential suggestions for the future have been made. Revascularization of teeth with IRR has promising results and should be considered a choice for treating IIR cases as an alternative to conventional root canal treatment.
http://www.ijsrdms.com/article_119544_ebf6d5c6d66f886a9e6d930fd7d0893f.pdf
2020-12-01
131
134
10.30485/ijsrdms.2020.245647.1082
Biocompatible material
Regenerative endodontics
Root resorption
Tricalcium silicate
Aamil
Ashraf
aamil.ashraf@yahoo.co.uk
1
Department of Endodontics, School of Dentistry, Universidad Europea de Madrid, Madrid, Spain
AUTHOR
Ruth
Pérez Alfayate
ruthip.alfayate@gmail.com
2
Department of Endodontics, School of Dentistry, Universidad Europea de Madrid, Madrid, Spain
LEAD_AUTHOR
[1] Patel S, Ford TP. Is the resorption external or internal?. Dental Update. 2007;34(4):218-29. https://doi.org/10.12968/denu.2007.34.4.218.
1
[2] Kaval ME. CASE REPORT Regenerative endodontic treatment of perforated internal root resorption: a case report.2018;51:128-137. doi:10.1111/iej.12784.
2
[3] Patel S, Ricucci D, Durak C, Tay F. Internal root resorption: a review. Journal of endodontics. 2010;36(7):1107-21. https://doi.org/10.1016/j.joen.2010.03.014.
3
[4] Thomas P, Krishna Pillai R, Pushparajan Ramakrishnan B, Palani J. An insight into internal resorption. International Scholarly Research Notices. 2014. http://dx.doi.org/10.1155/2014/759326.
4
[5] Nilsson E, Bonte E, Bayet F, Lasfargues JJ. Management of internal root resorption on permanent teeth. International journal of dentistry.2013. https://doi.org/10.1155/2013/929486.
5
[6] Trope M. Root resorption of dental and traumatic origin: classification based on etiology. Practical periodontics and aesthetic dentistry: PPAD. 1998;10(4):515-22.
6
[7] SAHARA N, OKAFUJI N, TOYOKI A, SUZUKI I, DEGUCHI T, SUZUKI K. Odontoclastic resorption at the pulpal surface of coronal dentin prior to the shedding of human deciduous teeth. Archives of histology and cytology. 1992;55(3):273-85. https://doi.org/10.1679/aohc.55.273.
7
[8] Calişkan MK, Türkün M. Prognosis of permanent teeth with internal resorption: a clinical review. Dental Traumatology. 1997;13(2):75-81. https://doi.org/10.1111/j.1600-9657.1997.tb00014.x.
8
[9] Ricucci D, Langeland K. Apical limit of root canal instrumentation and obturation, part 2. A histological study. International endodontic journal. 1998;31(6):394.
9
[10] Patel S, Kanagasingam S, Ford TP. External cervical resorption: a review. Journal of endodontics. 2009;35(5):616-25. https://doi.org/10.1016/j.joen.2009.01.015.
10
[11] Whitworth J. Dental root resorption. Part 2: internal inflammatory defects and understanding replacement resorption, the untreatable resorptive lesion. Endodontic Practice. 2004;2:7-11. DOI: 10.1111/j.1365-2591.2009.01592.x.
11
[12] Scarfe WC, Levin MD, Gane D, Farman AG. Use of cone beam computed tomography in endodontics. International journal of dentistry.2009. https://doi.org/10.1155/2009/634567.
12
[13] Maldonado A, Muñoz E. Manejo de una Reabsorción Radicular Interna en una Pieza Permanente. Reporte de Caso. Journal of Oral Research. 2015;4(4):275-81. DOI: https://doi.org/10.17126/joralres.2015.053.
13
[14] Li FC, Hung WC. Repair of a perforating internal resorption: two case reports. Journal of Dental Sciences. 2016;11(3):338-42. https://doi.org/10.1016/j.jds.2013.02.030.
14
[15] Bukhari S, Kohli MR, Setzer F, Karabucak B. Outcome of revascularization procedure: a retrospective case series. Journal of Endodontics. 2016;42(12):1752-9. https://doi.org/10.1016/j.joen.2016.06.021.
15
[16] Nosrat A, Seifi A, Asgary S. Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial. Journal of endodontics. 2011;37(4):562-7. https://doi.org/10.1016/j.joen.2011.01.011.
16
[17] Brito-Júnior M, Quintino AF, Camilo CC, Normanha JA, Faria-e-Silva AL. Nonsurgical endodontic management using MTA for perforative defect of internal root resorption: report of a long term follow-up. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2010;110(6):784-8. https://doi.org/10.1016/j.tripleo.2010.07.008.
17
[18] Andreasen JO, Farik B, Munksgaard EC. Long‐term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dental Traumatology. 2002;18(3):134-7. https://doi.org/10.1034/j.1600-9657.2002.00097.x.
18
[19] Macwan C, Deshpande A. Mineral trioxide aggregate (MTA) in dentistry: A review of literature. Journal of Oral Research and Review.
19
2014;6(2):71-4. DOI: 10.4103/2249-4987.152914.
20
[20] Saoud TM, Mistry S, Kahler B, Sigurdsson A, Lin LM. Regenerative endodontic procedures for traumatized teeth after horizontal root fracture, avulsion, and perforating root resorption. Journal of Endodontics. 2016;42(10):1476-82. https://doi.org/10.1016/j.joen.2016.04.028.
21
[21] Cohen S, Hargreaves KM, Berman L. Cohen’s Pathways of the Pulp. Mosby Elsivier 2011: 602–19.
22
[22] Murray PE, Garcia-Godoy F, Hargreaves KM. Regenerative endodontics: a review of current status and a call for action. Journal of endodontics. 2007;33(4):377-90. https://doi.org/10.1016/j.joen.2006.09.013.
23
[23] Paryani K, Kim SG. Regenerative endodontic treatment of permanent teeth after completion of root development: a report of 2 cases. Journal of Endodontics. 2013;39(7):929-34. https://doi.org/10.1016/j.joen.2013.04.029.
24
[24] Tambakad PB, Naidu J. Pulp and periodontal regeneration of an avulsed permanent mature incisor using platelet-rich plasma after delayed replantation: a 12-month clinical case study. Journal of Endodontics. 2016;42(1):66-71. https://doi.org/10.1016/j.joen.2015.07.016.
25
ORIGINAL_ARTICLE
Transmission Routes of SARS-CoV-2 in Dentistry: A Literature Review
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) might be transferred from animals to humans and then escalated into transmission from human to human. Since dentists are regarded as the greatest risk category of healthcare workers in getting COVID-19, this article summarizes the transmission routes of SARS-CoV-2, particularly in dentistry, to gather all the relevant details for dental professionals and healthcare workers. SARS-CoV-2 can be spread through four main ways in dental clinics: inhalation, direct contact, indirect contact, and mucosal interaction. SARS-CoV-2 can be transmitted through saliva, fecal-oral, and surgical smoke in an operating room.
http://www.ijsrdms.com/article_119798_f5ff9379268eb15ec6b2861f0f6e756e.pdf
2020-12-01
135
137
10.30485/ijsrdms.2020.252402.1088
COVID-19
Dentistry
Transmission
Maryam
Baghizadeh Fini
m.baghizadeh92@gmail.com
1
Department of Health Promotion, Oklahoma State University, Stillwater, OK, USA
LEAD_AUTHOR
[1] Fini MB. What dentists need to know about COVID-19. Oral Oncology. 2020;105:104741. https://doi.org/10.1016/j.oraloncology.2020.104741.
1
[2] Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P. A novel coronavirus from patients with pneumonia in China, 2019. New England Journal of Medicine. 2020; 382:727-733. DOI: 10.1056/NEJMoa2001017.
2
[3] Froum S, Strange M. COVID-19 and the problem with dental aerosols. Oral Medi-cine, Anesthetics and Oral-Systemic Connection [publicação na web]. 2020.
3
[4] Han P, Ivanovski S. Saliva—Friend and Foe in the COVID-19 Outbreak. Diagnostics. 2020;10(5):290. https://doi.org/10.3390/diagnostics10050290.
4
[5] Fini MB. Oral saliva and CVID-19. Oral Oncology. 2020;108:104821. https://doi.org/10.1016/j.oraloncology.2020.104821.
5
[6] Izzetti R, Nisi M, Gabriele M, Graziani F. COVID-19 transmission in dental practice: brief review of preventive measures in Italy. Journal of Dental Research. 2020;99(9):1030-38. https://doi.org/10.1177/0022034520920580.
6
[7] Jamal M, Shah M, Almarzooqi SH, Aber H, Khawaja S, El Abed R, Alkhatib Z, Samaranayake LP. Overview of transnational recommendations for COVID‐19 transmission control in dental care settings. Oral Diseases. 2020. https://doi.org/10.1111/odi.13431. DOI: 10.1111/odi.13431.
7
[8] Peng X, Xu X, Li Y, Cheng L, Zhou X, Ren B. Transmission routes of 2019-nCoV and controls in dental practice. International Journal of Oral Science. 2020;12(1):1-6. https://doi.org/10.1038/s41368-020-0075-9.
8
[9] Fallahi HR, Keyhan SO, Zandian D, Kim SG, Cheshmi B. Being a front-line dentist during the Covid-19 pandemic: A literature review. Maxillofacial Plastic and Reconstructive Surgery. 2020;42:1-9. https://doi.org/10.1186/s40902-020-00256-5.
9
[10] Van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, Tamin A, Harcourt JL, Thornburg NJ, Gerber SI, Lloyd-Smith JO. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. New England Journal of Medicine. 2020;382(16):1564-7. DOI: 10.1056/NEJMc2004973.
10
[11] Carrouel F, Conte MP, Fisher J, Gonçalves LS, Dussart C, Llodra JC, Bourgeois D. COVID-19: A recommendation to examine the effect of mouthrinses with β-cyclodextrin combined with citrox in preventing infection and progression.2020;9(4):1126. https://doi.org/10.3390/jcm9041126.
11
[12] Williams GH, Pollok NL, Shay DE, Barr CE. Laminar air purge of microorganisms in dental aerosols: prophylactic procedures with the ultrasonic scaler. Journal of dental research. 1970;49(6):1498-504. https://doi.org/10.1177/00220345700490065701.
12
[13] Harrel SK, Molinari J. Aerosols and splatter in dentistry: a brief review of the literature and infection control implications. The Journal of the American Dental Association. 2004;135(4):429-37. https://doi.org/10.14219/jada.archive.2004.0207.
13
[14] Hawel JE. Operating during COVID-19: Is there a risk of viral transmission from surgical smoke during surgery?. Canadian Journal of Surgery. 2020;63(3):E299-301. DOI:10.1503/cjs.007020.
14
ORIGINAL_ARTICLE
Mandibular Plasmocytoma: A Case Report of a Rare Entity
A plasmacytoma is a rare malignant, unifocal, monoclonal, neoplastic plasma cell proliferation tumor that usually occurs within the bone. In soft tissue, it is often seen, in which case the term extramedullary plasmacytoma is used. Some researchers believe this lesion is the least aggressive part of a plasma cell neoplasm spectrum that extends to multiple myeloma. The diagnosis of Solitary Plasmacytoma of Bone (SPB) is established by histopathological examination, and the histopathological presentation is identical to that of multiple myeloma. We present a case of a 55-year-old patient with the increased facial volume on the left side and a year of evolution, intraorally with exophytic and erythematous lesions and pseudomembranous plaques in the jaw on the left side, which at histopathological study resulted in plasmacytoma. The diagnosis was confirmed by immunohistochemistry. Oral and maxillofacial surgeons should know about this disease's etiology and clinical characteristics, and the oral cavity presence since a late treatment compromises the patient's life.
http://www.ijsrdms.com/article_120367_d82eef333f77f4b34e946e587288eeca.pdf
2020-12-01
138
140
10.30485/ijsrdms.2020.256693.1097
malignant
Plasmocytoma
Solitary Plasmocytoma of Bone
Alejandro
Cedeño
alejandrocedeno@hotmail.com
1
Department of Oral and Maxillofacial Surgery, School of Dentistry, Universidad del Zulia, Venezuela
AUTHOR
Gustavo
Bustamante
tavo238@gmail.com
2
Department of Oral and Maxillofacial Surgery, School of Dentistry, Universidad del Zulia, Venezuela
AUTHOR
Ariamay
Castrillo
ariamayc@gmail.com
3
Department of Oral and Maxillofacial Surgery, School of Dentistry, Universidad del Zulia, Venezuela
LEAD_AUTHOR
Salomon
Ramos
salomon_ramos@hotmail.com
4
Department of Oral and Maxillofacial Surgery, School of Dentistry, Universidad del Zulia, Venezuela
AUTHOR
[1] Meziane M, Boulaadas M, Essakalli L, Kzadri M, Harmouch A. Solitary plasmocytoma: ghost tumour?. International journal of oral and maxillofacial surgery. 2012;41(1):17-9. https://doi.org/10.1016/j.ijom.2011.06.019.
1
[2] Millesi W, Enislidis G, Lindner A, Schobel G, Ewers R, Drach J, Rath T. Solitary plasmocytoma of the mandible—a combined approach for treatment and reconstruction. International journal of oral and maxillofacial surgery. 1997;26(4):295-8. https://doi.org/10.1016/S0901-5027(97)80874-0.
2
[3] Kucukkurt S, Karan NB, Senguven B, Kahraman S. Solitary plasmacytoma of the mandible: report of two cases. Case Reports. 2016. http://dx.doi.org/10.1136/bcr-2015-214255.
3
[4] Rezaei F, Nazari H, Izadi B. Solitary plasmacytoma in the mandible resembling an odontogenic cyst/tumor. Case reports in dentistry. 2016. https://doi.org/10.1155/2016/3629047.
4
[5] An SY, An CH, Choi KS, Heo MS. Multiple myeloma presenting as plasmacytoma of the jaws showing prominent bone formation during chemotherapy. Dentomaxillofacial Radiology. 2013;42(4):20110143. doi: 10.1259/dmfr.20110143.
5
[6] Popovski V, Dvojakovska S, Benedetti A, Panchevski G, Stamatoski A, Janevska V. Mandibular involvement of plasmacytoma–Uncommon case report of rare entity. Annals of Medicine and Surgery. 2019;45:95-7. https://doi.org/10.1016/j.amsu.2019.07.021.
6
[7] Marotta S, Di Micco P. Solitary plasmacytoma of the jaw. Journal of blood medicine. 2010;1:33-36. doi:10.2147/JBM.S8385.
7
[8] Lombardo EM, Maito FL, Heitz C. Solitary plasmacytoma of the jaws: therapeutical considerations and prognosis based on a case reports systematic survey. Brazilian Journal of Otorhinolaryngology. 2018;84(6):790-8. https://doi.org/10.1016/j.bjorl.2018.05.002.
8
[9] Grammatico S, Scalzulli E, Petrucci MT. Solitary plasmacytoma. Mediterranean Journal of Hematology and Infectious Diseases. 2017;9(1). doi: 10.4084/MJHID.2017.052.
9
[10] Finsinger P, Grammatico S, Chisini M, Piciocchi A, Foà R, Petrucci MT. Clinical features and prognostic factors in solitary plasmacytoma. British journal of haematology. 2016;172(4):554-60. https://doi.org/10.1111/bjh.13870.
10
ORIGINAL_ARTICLE
CBCT Management of Previously Treated Mandibular Incisor with Extensive Internal Root Resorption: A Case Report
This case report describes a central mandibular incisor's retreatment. Follow-up with perforating internal root resorption managed using a reciprocating file and obturated with down-pack and backfill technique, a surgical approach to seal the perforation. The medical history was non-contributory, and he had a history of traumatic injury resolved by a general dentist one year before. Tooth (4.1) presented pain and, after inspection and exploration, the clinical diagnosis was established as a previously-treated tooth with apical periodontitis. During periodic clinical and radiographic follow-up, the patient remained symptom-free, meeting functional expectations after eight years. Understanding the pathology and knowing the techniques to manage it could help recover the function of teeth considered lost.
http://www.ijsrdms.com/article_120924_68ab3a7ad6f35e9d568b575a6fcbc834.pdf
2020-12-01
141
144
10.30485/ijsrdms.2020.254227.1095
Instrumentation
Root Canal Obturation
Root resorption
Ruth Pérez
Alfayate
ruthip.alfayate@gmail.com
1
Department of Endodontics, School of Dentistry, Universidad Europea de Madrid, Madrid, Spain
LEAD_AUTHOR
Ana
Suarez
anasuarez@yahoo.com
2
Department of Clinical Dentistry, School of Dentistry, Universidad Europea de Madrid, Madrid, Spain
AUTHOR
Juan
Algar Pinilla
juanap2000@gmail.com
3
Department of Endodontics, School of Dentistry, Universidad Europea de Madrid, Madrid, Spain
AUTHOR
[1] Gulabivala K, Searson LJ. Clinical diagnosis of internal resorption: an exception to the rule. International endodontic journal. 1995;28(5):255-60. https://doi.org/10.1111/j.1365-2591.1995.tb00310.x.
1
[2] Andreasen JO. Luxation of permanent teeth due to trauma A clinical and radiographic follow‐up study of 189 injured teeth. European Journal of Oral Sciences. 1970;78(1‐4):273-86. https://doi.org/10.1111/j.1600-0722.1970.tb02074.x.
2
[3] Rabinowitch BZ. Internal resorption. Oral Surgery, Oral Medicine, Oral Pathology. 1972;33(2):263-82. https://doi.org/10.1016/0030-4220(72)90396-9.
3
[4] Patel S, Ricucci D, Durak C, Tay F. Internal root resorption: a review. Journal of endodontics. 2010;36(7):1107-21. https://doi.org/10.1016/j.joen.2010.03.014.
4
[5] Cabrini RL, Maisto OA, Manfredi EE. Internal resorption of dentine: histopathologic control of eight cases after pulp amputation and capping with calcium hydroxide. Oral Surgery, Oral Medicine, Oral Pathology. 1957;10(1):90-6. https://doi.org/10.1016/S0030-4220(57)80120-0.
5
[6] Penido RS, Carrel R, Chialastri AJ. The anachoretic effect in root resorption: report of case. The Journal of pedodontics. 1980;5(1):85.
6
[7] Walton RE, Leonard LA. Cracked tooth: an etiology for “idiopathic” internal resorption?. Journal of endodontics. 1986;12(4):167-9. https://doi.org/10.1016/S0099-2399(86)80056-5.
7
[8] Silveira FF, Nunes E, Soares JA, Ferreira CL, Rotstein I. Double ‘pink tooth’associated with extensive internal root resorption after orthodontic treatment: a case report. Dental Traumatology. 2009;25(3):e43-7. https://doi.org/10.1111/j.1600-9657.2008.00755.x.
8
[9] Pérez-Alfayate R, Mercadé M, Vera J. Relationship between internal root resorption and dens in dente. Journal of Clinical and Experimental Dentistry. 2020;12(8):e800-e804. doi: 10.4317/jced.56944.
9
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