ORIGINAL_ARTICLE
Comparison of Oral Manifestations in Patients with Hyperthyroidism and Hypothyroidism in Outpatient Clinic of Razi Hospital in Rasht City in 2018
Background and aim: Comparison of oral manifestations in patients with hyperthyroidism and hypothyroidism in an outpatient clinic of Razi Hospital in Rasht City.Materials and methods: This descriptive-analytical study was performed on 121 patients with hypothyroidism and 55 patients with hyperthyroidism referred to an outpatient Clinic of Razi Hospital in Rasht City under the supervision of an endocrinologist. Patients' information was recorded in a questionnaire after the oral examination. Data were described by using SPSS 22.Results: The mean age of patients in this study was 44.3±13.7 years. 47.1% of hypothyroidism and 21.8% of hyperthyroidisms had a congress tongue (p<0.0001). Macroglossia was 43.8% in hypothyroidism and 14.5% in hyperthyroidism patients (approximately 3 times) (p <0.0001). Only 5% of hypothyroid patients were oral lichen planus, while none of the hyperthyroidisms had oral lichen planus (p=0.101).Conclusion: As discussed in this study, oral manifestations in thyroid patients, especially hypothyroidisms, were observed. They considered the possibility of manifestations such as lichen planus, xerostomia, and knowledge of recognizing the clinical signs of these lesions. The interaction between dentists and endocrinologists, accurate follow up of these patients, and control of their complications and considerations during work with these patients to prevent the possible complications should be paying attention.
http://www.ijsrdms.com/article_89755_26161156a9c59da0f7c22e70d75da8b2.pdf
2019-06-01
1
6
10.30485/ijsrdms.2019.89755
hyperthyroidism
hypothyroidisms
Oral lichen planus
Mohadese
Barri Dizaj
mohaddesebarri@yahoo.com
1
School of Dentistry, Guilan University of Medical sciences, Rasht, Iran
LEAD_AUTHOR
Zahra
Abdolkarimpour
z.abdolkarimpouri@yahoo.com
2
Department of Oral Medicine, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran
AUTHOR
Maryam
Rabiei
m.rabie@yahoo.com
3
Department of Oral Medicine, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran
AUTHOR
Mojtaba
Mehrdad
m.mehrdad@yahoo.com
4
Department of Internal Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
AUTHOR
Chandna S, Bathla M. Oral manifestations of thyroid disorders and its management. Indian journal of endocrinology and metabolism. 2011; 15 (Supp l2): S113.
1
Little j. Thyroid disorders:Part II,hypothyroidism and thyroiditis. 2006;102: 148-53.
2
Klein I. Thyroid hormone and the cardiovascular system. Am J Med1990; 88:631-7.
3
Liu J, Duan Y. Saliva: A potential media for disease diagnostics andmonitoring. Oral Oncology. 2012; 48(7):569-77.
4
Larsen PR, Davies TF, Hay ID. The thyroid. In: Williams RH,Wilson JD,Foster DW, Kronenberg HM, eds. Williams textbook ofendocrinology. 9th ed. Philadelphia: Saunders; 1998:389-416.
5
Rodríguez ME, García MA, Flores IS. Congenital hypothyroidism and its oral manifestations. Revista Odontológica Mexicana. 2014;18(2):133-8.
6
Goldman L, Schafer AI. Cecil medicine. 24th ed. Philadelphia: Elsevier Health Sciences; 2011.
7
Young ER. The thyroid gland and the dental practitioner. J Can DentAssoc 1989; 55: 903-7.
8
Monea A, Elod N, Sitaru A, Stoica A, Monea M. Can thyroid dysfunction induce periodontal disease? European Scientific Journal, ESJ. 2014; 10(15).
9
Al-Hashimi I, Schifter M, Lockhart PB, Wray D, Brennan M, Migliorati CA, Axéll T, Bruce AJ, Carpenter W, Eisenberg E, Epstein JB. Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2007; 103: S25-e1.
10
Ismail SB, Kumar SK, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. Journal of oral science. 2007; 49(2):89-106.
11
Robledo-Sierra J, Landin-Wilhelmsen K, Nyström HF, Mattsson U, Jontell M. Clinical characteristics of patients with concomitant oral lichen planus and thyroid disease. Oral surgery, oral medicine, oral pathology and oral radiology. 2015; 120(5):602.
12
Robledo‐Sierra J, Mattsson U, Jontell M. Use of systemic medication in patients with oral lichen planus–a possible association with hypothyroidism. Oral diseases. 2013 Apr 1; 19(3):313-9.
13
Lo Muzio L, Santarelli A, Campisi G, Lacaita M, FaviaG. Possible link between Hashimoto's thyroiditis and orallichen planus: a novel association found. Clin Oral Investig.2013; 17: 333-336.
14
Siponen M, Huuskonen L, Läärä E, Salo T. Associationof oral lichen planus with thyroid disease in a Finnishpopulation: aretrospective casecontrol study. Oral SurgOral Med Oral Pathol Oral Radiol Endod. 2010; 110:319-324, 50.
15
Robledo-Sierra J, Landin-Wilhelmsen K, Nyström HF, Mattsson U, Jontell M. Clinical characteristics of patients with concomitant oral lichen planus and thyroid disease. Oral surgery, oral medicine, oral pathology and oral radiology. 2015 Nov 30; 120(5):602-8.
16
ORIGINAL_ARTICLE
Dental Students’ Perceptions of Learning Environment in Guilan University of Medical Sciences
Background and aim: This study aimed to assess dentistry students' understanding of the educational environment of Guilan University of Medical Sciences in two Basic and clinical fields.Materials and methods: This cross-sectional descriptive study was conducted in the academic year of 2016-17 at the Faculty of Dentistry, Guilan University of Medical Sciences. For this purpose, a sample of 190 students was selected in both the primary and clinical fields. Assess the learning environment, DREEM's Assessment Questionnaire (DREEM) questionnaire consisted of 50 questions in 5 areas of learning, professors, student perception of their ability, educational background, and student perception of their social status. Data were analyzed using descriptive statistics and the Mann-Whitney test in SPSS Ver 16 software.Results: The findings showed that the average total score of educational and learning environments in the Basic Section was 108.22 in the maximum of 200, and the Clinical Section was 111.03, which means a favorable threshold. In Basic Section, the lowest average score was 15.28 for self-social understanding, and the highest score was 26.09 for the educational atmosphere, while in the Clinical Section, the lowest and the highest mean scores were 15.81and 26.56 related to the same field of Basic Section.Conclusion: The results showed that the perception of students at two different levels of Basic Science and Clinical Section from the educational environment is favorable, but more attention of the faculty members to reducing the stress of the environment and creating an appropriate environment is essential.
http://www.ijsrdms.com/article_89756_24e2ed831556ce3d079a79514c2a5d55.pdf
2019-06-01
7
12
10.30485/ijsrdms.2019.89756
Dentistry
Educational environment
Training course
Samira
Jamali
samira.jamali90@yahoo.com
1
Student Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran
LEAD_AUTHOR
Bardia
Vadiati Saberi
b.vadiati@yahoo.com
2
Department of Periodontology, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran
AUTHOR
Mahdokht
Taheri
m.taheri@yahoo.com
3
Education Development Center, Guilan University of Medical Sciences, Rasht, Iran
AUTHOR
Miles S, Leinster S. Mwdical student’s perception of their educational environment: expected versus actual perception .Med Edac 2007; 41:265-72.
1
Shreemath S, MayyA,RoffS. Student’s perception of education environment a achievers of academic achievers &under. Achievers at Kasturba Medical College, India Education for Health 2004; 17(3):280- 291.
2
Aghamolaei T,Fazel I. Medical Student’s Perceptions of the Educational Enviroment at an Iranian Medical Science University. BMN Medical Education. 2010; (1): 10- 87.
3
Abraham RR,Ramnarayan, K,PallathV,Torke, S,Madharan M, Roffs. Preceptions of academic achivers and under achivers regarding learning environment of Melaka Manipal Medical College (Manipal Compus), Manipal India, using DREEM the Inventory. South East Asia Journal of Medical education. 2008; 18-24.
4
Roff S. The Dundee Ready Educational Environment Measure (DREEM) a generic instrument for measuring students' perceptions of undergraduate health professions curricula. Medical Teacher. 2005; 27(4):322-5.
5
Soltani Arabshahi K KJ, Sobuti B. The Educational Environment of Main Clinical Wards in Educational Hospitals Affiliated to Iran university of Medical Sciences: Learners Viewpoints Based on DREEM model Iranian Journal of Medical Education 2008; 8(1):43-9 (Persian).
6
McAleer SR, Sean. What is educational climate? Medical Teacher. 2001; 23(4):333-334.
7
Soltani Arabshahi K, Moosavi M, Koohpayehzade J, BigdeliSh, Hatami K. Assessment of Educational Environment at Main Clinical Wards in Teaching Hospitals Affiliated to Iran University of Medical Sciences :Stagers &Interns Viewpoints Based on Modified DREEM.2015; 21(129):58-67.
8
Moshki M, Dehnoalian A, Shareinia M. Medical Students’ Perceptions of Learning Environments in Gonabad University of Medical Sciences. 2014; 7(16):116-126.
9
Myint, K., et al. "Dental Students’ Educational Environment and Perceived Stress: The University of Malaya Experience." The MalaysianJournal of Medical Sciences: MJMS. 2016; 23(3): 49.
10
Patil, A. A. and V. L. Chaudhari. "Students’ perception of the educational environment in medical college: a study based on DREEM questionnaire." Korean Journal of Medical Education. 2016; 28(3): 281.
11
Rehman, R., et al. "Students’ perception of educational environment at Aga Khan University Medical College, Karachi, Pakistan." Pakistan Journal of Medical Sciences. 2016; 32(3): 720.
12
Moshki, M., et al. "Medical students' perceptions of learning environments in Gonabad University of Medical Science." Journal of Medical Education Development. 2014; 7(16): 116-126.
13
Bay Jr, B. E. and H. Subido "DREEM is real: dental students learning environment in an Asian University." International Journal of Academic Research in Business and Social Sciences. 2014; 4(7): 620.
14
Pai, P. G., et al. "Medical students’ perception of their educational environment." Journal of clinical and diagnostic research: JCDR. 2014; 8(1): 103.
15
Zahra Fatehi, Mohammad Asadpour, Hamid Bakhshi. Study of the quality of learning environment from the viewpoint of nursing and midwifery students of nursing and midwifery faculty of Rafsanjan University of medical sciences. Summary of Articles the First National Conference on Methods of Teaching and Learning in the Area and University. June 23, 2015; 1 (1).
16
Aghili, H., et al. "evaluation of the effect of early clinical exposure on professional attitude of dental students of Shahid Sadoughi University of Medical Sciences in 2013.
17
Al-Kabbaa, A. F., et al. "Perception of the learning environment by students in a new medical school in Saudi Arabia: Areas of concern." Journal of Taibah University Medical Sciences. 2012; 7(2): 69-75.
18
Taramsaria, M. R., et al. "Assessment of students’ perceptions of educational environment in clinical wards of university hospitals at an Iranian Medical Sciences University." Procedia-Social and Behavioral Sciences. 2012; 46: 715-720.
19
Jabarifar, S. E., et al. "Assessment of Isfahan Dentistry Students about learning-teaching environment." Iranian Journal of Medical Education. 2011; 10(5): 860-867.
20
ORIGINAL_ARTICLE
The Comparison of the Effect of Photodynamic Therapy Using two Photosensitizer Indocyanine Green and Methylene Blue on the Colony Count of Staphylococcus Aureus (In Vitro)
Background and aim: Contamination of microorganisms, including Staphylococcus Aureus, in oral saliva and oral tissues, is a common problem. Therefore, in this study, photodynamic therapy's effect on the number of oral Staphylococcus Aureus colonies. Was evaluated using two indices of Indocyanine Green and Methylene Blue with sensitizer with Chlorhexidine mouthwash.Materials and methods: In the first stage, a new culture of ATCC St.Aureus 25923 was performed. Colonies of Staphylococcus Aureus were counted. The teeth were randomly divided into four groups: the first group was Methylene Blue, and the second group was subjected to 2% Indocyanine Green. All samples from both groups were sampled before laser irradiation and colonized in the culture medium for 24 hours. The third group of teeth was immersed in 2% Chlorhexidine mouthwash and sampled. The fourth group was considered as the control group. Also, Post hoc analysis was used for comparing before and after treatment in each group.Results: This study showed that all three experimental groups reduced the number of Staphylococcus Aureus colonies. However, Indocyanine Green and Methylene Blue did not significantly decrease the number of colonies before and after treatment (p> 0.05), but Chlorhexidine caused a significant decrease in the number of Staphylococcus colony Aureus (p <0.05).Conclusion: The results of this study showed that all three groups of Chlorhexidine, Indocyanine Green and Methylene Blue, reduced the colony count of Staphylococcus Aureus, although the effects of the reduction of Staphylococcus Aureus were significantly more severe than Chlorhexidine.
http://www.ijsrdms.com/article_89757_85305520246eba8ca1edea5ebc438e50.pdf
2019-06-01
13
17
10.30485/ijsrdms.2019.89757
Chlorhexidine
Indocyanine Green
Methylene blue
Photodynamic therapy
Staphylococcus aureus
Zahra
Sanaei
zahrasanaei12@yahoo.com
1
Faculty of Dentistry, Islamic Azad University, Dental Branch, Tehran, Iran
LEAD_AUTHOR
Arash
Azizi
arash.azizi@yahoo.com
2
Department of Oral Medicine, Faculty of Dentistry, Islamic Azad University, Dental Branch, Tehran, Iran
AUTHOR
Arash
Rahimi
rahimi.a1397@yahoo.com
3
Department of Biophysics, Faculty of Dentistry, Islamic Azad University, Dental Branch, Tehran, Iran
AUTHOR
Wilson M. Bacterial biofilms and human disease. Science progress2001; 84(3):235-54.
1
Wilson P, Wilson PM. Dental plaque revisited: oral biofilms in health and disease. Journal of Periodontal Research1998; 33(7):438-439.
2
Jenkinson HF. Adherence andaccumulation of oral streptococci. Trends in microbiology 1994; 2(6):209-12.
3
Pires JR, Rossa Junior C, Pizzolitto AC. In vitro antimicrobial efficiency of a mouthwash containing triclosan/gantrez and sodium bicarbonate. Brazilian oral research 2007; 21(4):342.
4
Derks A, Frencken J, Bronkhorst E, Kuijpers-Jagtman AM, Katsaros C. Effect of chlorhexidine varnish application on mutans streptococci counts in orthodontic patients. American Journal of Orthodontics and Dentofacial Orthopedics 2008; 133(3):435-9.
5
Pitten F-A, Kramer A. Antimicrobial efficacy of antiseptic mouthrinse solutions. European journal of clinical pharmacology 1999; 55 (2):95- 100.
6
Soukos NS, Goodson JM. Photodynamic therapy in the control of oral biofilms. J Periodontology2011; 55(1):143-66.
7
Dougherty TJ. An update on photodynamic therapy applications. Journal of clinical laser medicine & surgery 2002; 20(1):3-7.
8
Wainwright M. Photodynamic antimicrobial chemotherapy (PACT). Journal of antimicrobial chemotherapy.1998; 42(1):13-28.
9
Pfitzer A,Sigusch BW, Alberecht V,GI ockmann E. Killing of periodonto pathogenic bacteria by photodynamic therapy. Jperiodontal 2004; 75:1343-1349.
10
Wilson M. Lethal photosensitization of oral bacteria and its potential application in the photodynamic therapy of oral infections. Photochemical and photobiological sciences2004; 3:412-418. 12. Dougherty TJ,Gomer CJ,Hen derson BW,Jori G, kessel D, Korbelik M,Moan J,Peny Q.photodynamic therapy.J Nat cancer Inst.1998;90:889- 905.
11
Ochsner M. Photo physical and photobiological process in the photodynamic therapy of tumors. J photochemphotobiol B 1997; 39:1-8.
12
Moan J, Berg K. The photo degration of porphyrins in cells that can be used to estimate the life time of singlet oxygen.photochemphotobial 1991; 53:549-53.
13
Peng Q, Moan J, Nesland J. Correlation of subcellular and intratumoral photosensitizer localization with ultra structural features after photodynamic therapy. Ultrastructpatol 1996; 20:109-29.
14
Raghavendra M, Koregol A, Bhol S. Phtodynamictherapy: a target therapy in periodontics. Australian Dental Journal 2009;54(1):102-190.
15
Allison P, Baganto V, Cuenca R, Downie G, Sibata C. The future of photodynamic therapy in oncolony.FutureOncol 2006; 2:53-71.
16
Buytaert E, Dewaele M, Agostinis P. Molecular effectors of multiple cell death pathways initiated by photodynamic therapy. BiochimBiophysActa 2007; 1976:86-107.
17
Wein Wright M. Photodynamic antimicrobial chemotherapy.J An imicrobial chemother. 1998; 42:13-28.
18
Sharman WM, Allen CM,Van Leir JE. Photo dynamic Therapeutic :basic and clinical applica ons.Drug Discov 1999;4:507-514.
19
Uzdensky AB,Dergacheva OY, Zahavorokova AA,Reshetnikov Av, Ponomarev GV. photodynamic e ect of novel chlorin e6 deriva ves on a single nerv cell.Life sci 2004;73:2185-2197.
20
Gottumukkala S, Mantena S. Photodynamic in antimicrobial periodontal therapy. Indian J Oral Sci 2012; 3:8-12.
21
Baumler W, Abels C, Karrer S, Weiss T, Mess Mann H, Landthaler M. Photo- oxidative killing of human colonic cancer cells using indocyanine Green and infrared light. Br J Cancer 1999; 80:360-363.
22
Hope CK, Wilson M. Indication of lethal photosensitization in biofilms using a confocal scanning laser as the excitation source.JAntimicrob 2006; 57(6):1227-1230.
23
Sreenivasan p, Gihins E.Effects of low dose chlrohexidine mouthrinses on oral bacteria and salivary microflora including those producing hydrogen sul de.Jod 2004;19:309-313.
24
Aparecida Pereira C, Borges Pereira Costa A, Moura Carreira C. CamposJunqueriraJ,Olavo Cardoso JorgaA.photodynamic inactivation of streptococcus mutans and streptococcus sanguinis bio ims:invitro. Laser Med Sci 2013 ;28:859-864.
25
Vahabi S, FekrazadR, AyremlouS,TaheriS, ZangenehN. the effect of antimicrobial photodynamic therepy with radachlorin and Touidine Blue on streptococcus mutans.J Dent (Tehran) 2011;8(2):48-54. 28. Vaziri S, Kangarlou A,Shahbazi R,Nazari M.comparesion of the bacterial efficiency of photodynamic therepy 5.5 % sodium hypochlorite and 2% chlorhexidineagaint enterococcus faecalis in root canals: an in vitro study. DentRes J 2012;9(5):613-618.
26
Michael R.effectiveness of antimicromial photodynamic therepy on Staphylococcus Aureus using phenothiazinium dye with red lasar.J SPIE 2015; 10:9309.
27
Chein-Ming H,Yen-Ha0 H.Aminolevulinic acid induced photodynamic inactivation on Staphylococcus Aureus and pseudomonas aeruginosa.J of food and drug Analysis 2014;22(3):350-355.
28
Renata T,YasinKH,FabioR,MauroS,peterJ.antimicrobial susceptibility of photodynamic therepy (UVA/riboflavin) againt Staphylococcus Aureus .JSciElo 2012;6:75.
29
ORIGINAL_ARTICLE
The Ability of Cone Beam Computed Tomography to Predict Osteopenia and Osteoporosis via Radiographic Density Derived from Cervical Vertebrae
Background and Aim: Osteoporosis (OP) is defined as a bone density-related disorder identified by a reduction of the microstructure quality of bone with increased fracture risk. The current study aimed to evaluate the ability of the cone-beam computed tomography (CBCT) imaging method to predict osteoporosis and osteopenia using Radiographic Density (RD) values derived from cervical vertebrae.Materials and methods: This study was a descriptive-cross sectional study conducted on 54 research units suffering from osteopenia and osteoporosis in the hip, aged 42-72 years. Finally, the values of RD from the lateral mass of the first cervical vertebra on both right and left side and dens and body of the second cervical vertebrae were calculated by NNT viewer software.Results: Comparing all values of RD obtained from the first cervical vertebrae and second cervical vertebrae revealed a statistically significant difference between the three groups (P-value <0.05).It was also found that the most accurate prediction of osteoporosis was related to the values of RD from body of C2 so that the accuracy equals 99% and cut-off point (Cut-point) of it was 293, respectively. Also, the most accurate prediction of hip-related osteopenia was for the values of RD from the body of C2 so that the accuracy is88%, and the cut-off point is also 375.Conclusion: According to the findings of this study, osteoporosis and osteopenia status can be predicted through RD value amounts related to a body part of the second cervical vertebra, which was more precise than the other parts.
http://www.ijsrdms.com/article_89758_9135a64177817714b5cdf69ee090aee0.pdf
2019-06-01
18
22
10.30485/ijsrdms.2019.89758
CBCT
cervical vertebra
Osteoporosis
Radiography
Salar
Payahoo
goendo90@gmail.com
1
Department of Oral and Maxillofacial Radiology, Dental School, Urmia University of Medical Sciences, Urmia, Iran
AUTHOR
Golchin
Jabbari
jabbarign@gmail.com
2
Department of Endodontics, Dental School, Urmia University of Medical Sciences, Urmia, Iran
LEAD_AUTHOR
Consensus, N., Development panel on osteoporosis: prevention, diagnosis and therapy. Jama, 2001. 285(6): p. 785-795.
1
Riera-Espinoza, G., Epidemiología de la osteoporosis en Latino América. Salud pública de México, 2009. 51: p. s52-s55.
2
Johnell, O. and J. Kanis, Epidemiology of osteoporotic fractures. Osteoporosis international, 2005. 16(2): p. S3-S7.
3
Cummings, S.R. and L.J. Melton, Epidemiology and outcomes of osteoporotic fractures. The Lancet, 2002. 359(9319): p. 1761-1767.
4
Cooper, C., Epidemiology of osteoporosis. Osteoporosis International, 1999. 9(8): p. S2-S8.
5
Pajouhi, M., et al., Bone Mineral Density in 10 to75 Year-Old Iranian Healthy Women: Population Base Study. Iranian Journal of Public Health, 2004: p. 57-63.
6
Link, T.M., Osteoporosis imaging: state of the art and advanced imaging. Radiology, 2012. 263(1): p. 3-17.
7
Siu, W.S., L. Qin, and K.S. Leung, pQCT bone strength index may serve as a better predictor than bone mineral density for long bone breaking strength. Journalof bone and mineral metabolism, 2003. 21(5): p. 316- 322.
8
Eastell, R., Treatment of postmenopausal osteoporosis. New England journal of medicine, 1998. 338(11): p. 736-746.
9
Organization, W.H., Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: report of a WHO study group [meeting held in Rome from 22 to 25 June 1992]. 1994.
10
Lewiecki, E.M., et al., Official positions of the international society for clinical densitometry. The Journal of Clinical Endocrinology & Metabolism, 2004. 89(8): p. 3651-3655.
11
Nomura, Y., et al., Stability of voxel values from cone‐beam computed tomography for dental use in evaluating bone mineral content. Clinical oral implants research, 2013. 24(5): p. 543-548.
12
Mozzo, P., et al., A new volumetric CT machine for dental imaging based on the cone-beam technique: preliminary results. European radiology, 1998. 8(9): p. 1558-1564.
13
Bornstein, M.M., et al., Cone beam computed tomography in implant dentistry: a systematic review focusing on guidelines, indications, and radiation dose risks. International journal of oral & maxillofacial implants, 2014. 29.
14
Hua, Y., et al., Bone quality assessment based on cone beam computed tomography imaging. Clinical oral implants research, 2009. 20(8): p. 767-771.
15
Spin-Neto, R., E. Gotfredsen, and A. Wenzel, Standardized method to quantify the variation in voxel value distribution in patient-simulated CBCT data sets. Dentomaxillofacial Radiology, 2014. 44(2): p. 20140283.
16
Kasturi, G.C., D.X. Cifu, and R.A. Adler, A review of osteoporosis: Part I. Impact, pathophysiology, diagnosis and unique role of the physiatrist. PM&R, 2009. 1(3): p. 254-260.
17
Genant, H., K. Engelke, and S. Prevrhal, Advanced CT bone imaging in osteoporosis. Rheumatology, 2008. 47(suppl 4): p. iv9-iv16.
18
Naitoh, M., et al., Measurement of mandibles with micro focus x-ray computerized tomography and compact computerized tomography for dental use. International Journal of Oral & Maxillofacial Implants, 2004. 19(2).
19
White, S.C. and M.J. Pharoah, The evolution and application of dental maxillofacial imaging modalities. Dental Clinics of North America, 2008. 52(4): p. 689-705.
20
Barngkgei, I., I. Al Haffar, and R. Khattab, Osteoporosis prediction from the mandible using cone-beam computed tomography. Imaging science in dentistry, 2014. 44(4): p. 263-271.
21
Pauwels, R., et al., CBCT-based bone quality assessment: are Hounsfield units applicable? Dentomaxillofacial Radiology, 2014. 44(1): p. 20140238.
22
ORIGINAL_ARTICLE
The Relationship between Serum Uric Acid Level and Pulmonary Artery Hypertension in Patients with Chronic Renal Failure
Background and aim: Uric Acid is the final production of purine metabolism. The serum concentration of this substance is related to purine metabolism and renal clearance. Pulmonary hypertension (PH) in patients with CKD may be induced or aggravated by left ventricular (LV) disorders. The presence of risk factors typical to CKD is including volume overload, an arteriovenous fistula, sleep-disordered breathing. Exposure to dialysis membranes, endothelial dysfunction, vascular calcification and stiffening, and severe anemia.Materials and methods: In this study relation between Uric Acid levels and PH in 70 patients with non-dialysis renal failure (41 females, 29 males) with a mean age of 61.71±12.44 years were assessed. The required information is extracted from the patients' records based on the questionnaire. Finally, the results are analyzed according to the SPSS program.Results: PH was defined as a PASP ≥ 35 mmHg by echocardiography. 36 CKD patients had PH (51.4%). Average Uric Acid levels in patients with PH were significantly higher than healthy controls (p = 0.003). For 1mmHg increase Uric Acid, 0.94 mmHg in pulmonary artery pressure level will increase. There was no significant difference between patients with PH and patients without PH according to age, gender, BMI, MAP, GFR, EF, RV size & function, LV diastolic dysfunction, SMRV, and TAPSE.Conclusion: Control of high Uric Acid levels and the treatment of risk factors of PH for prevention PH seems reasonable.
http://www.ijsrdms.com/article_89759_8f04a4186a40986ba830dd4dadfd78c7.pdf
2019-06-01
23
25
10.30485/ijsrdms.2019.89759
Chronic renal failure
PULMONARY ARTERIAL HYPERTENSION
Serum Uric Acid
Somaye
Jamali
somaye_jamali@yahoo.com
1
Department of Internal Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
Farokhlegha
Ahmadi
2
Department of Nephrology, Nephrology Research Center, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Mitra
Mahdavi-Mazdeh
mitra.m2019@gmail.com
3
Iranian Tissue Bank and Research Center, Imam Khomeini Hospital Complex, Tehran, Iran
AUTHOR
Anahita
Tavoosi
dr.tavoosi2020@gmail.com
4
Cardiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Gertler MM, Garn SM, Levine SA. Serum uric acid in relation to age and physique in health and in coronary heart disease. Ann Intern Med 1951; 34: 1421-3.
1
Anker SD, Doehner W, Rauchhaus M, et al.Uric acid and survival in chronic heart failure: Validation and application in metabolic, functional, and hemodynamic staging. Circulation 2003; 107:1991-7.
2
Oya H, Nagaya N, Satoh T, et al. Hemodynamic correlates and prognostic significance of serum uric acid in adult patients with Eisenmenger syndrome. Heart 2000; 84:53-8.
3
Braghiroli A, Sacco C, Erbetta M, Ruga V, and Donner CF, Overnight urinary acid: creatinine ratio for detection of sleep hypoxia: Validation study in chronic obstructive pulmonary disease and obstructive sleep apnea before and after treatment with nasal continuous positive airway pressure. Am Rev Respir Dis 1993; 148:173 -8.
4
Lawrence G. Rudski, MD, FASE, Chair, Wyman, et al Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010; 23:698.
5
Abdelwhab S and Elshinnawy S .Pulmonary hypertension in chronic renal failure patients. Am. J. Nephrol. 2008; 28: 990-997.
6
Kiykim AA, Horoz M, Ozcan T, Yildiz I, et al. Pulmonary hypertension in hemodialysis patients without arteriovenous fistula: the effect of dialyzer composition. Ren. Fail. 2010; 32: 1148-1152.
7
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ORIGINAL_ARTICLE
Evaluation of the Community Periodontal Index of Treatment Needs (CPITN) in Dialysis Patients Referring to the Hemodialysis Department of 5th Azar Hospital in Gorgan City, 2017- 2018
Background and aim: Patients who undergo hemodialysis treatment have problems like periodontal diseases because of the side effects of their illness or their drugs. This study evaluates periodontal problems and their therapeutic needs by assessing the CPITN index in patients with dialysis to take a step toward the periodontal health of these patients.Materials and methods: This study was performed on 55 dialysis Patients admitted to the ward of hemodialysis of the 5th Azar Gorgan Hospital, who were eligible. After giving necessary explanations, the day after their dialysis treatment, they received a periodontal examination. We used SPSS18 for statistical analysis of the data.Results: Measurement of the CPITN index showed that normal periodontal status (code 0): 7.3%, bleeding on probing (code 1): 10.9%, dental calculus (code 2): 49.1%, low depth pockets (code 3): 27.3%, deep pockets (code 4): 5.5%. In other words, four patients (7.3%) didn’t need any treatments, 6 of them (10.9%) needed oral hygiene instruction, 42 of them (76.4%) needed oral hygiene instruction and scaling, and 3 of them (5.5%) needed advanced periodontal treatments.Conclusion: This study shows that most hemodialysis patients were not in a good situation for periodontal diseases and needed treatments. Also, it was found that the CPITN index does not matter on the sex or age, but it has a meaningful relationship with the duration of dialysis treatment; in other words, the longer duration of dialysis treatment causes more periodontal problems.
http://www.ijsrdms.com/article_89760_31a612ab77d9c5527f4e58f6321a55e9.pdf
2019-06-01
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10.30485/ijsrdms.2019.89760
CPITN
Hemodialysis
Periodontal Diseases
Elaheh
Ramezani
elahehramezanie@yahoo.com
1
Faculty of Dentistry, Golestan University of Medical Sciences, Gorgan, Iran
LEAD_AUTHOR
Amir Reza
Ahmadinia
amirrezaahmadin@yahoo.com
2
Department of Periodontics, Faculty of Dentistry, Golestan University of Medical Sciences, Gorgan, Iran
AUTHOR
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